Naphazoline Nitrate
LC4192 Naphazoline nitrate
suitable for use as an active pharmaceutical ingredient api Ph Eur,BP
Order number | Packaging | Quantity | Price |
AC31192 | Plastic bottle | 1 kg | Inquire |
Product information | |
Grade | Ph Eur,BP |
Synonyms | 2-(1-Naphthylmethyl)imidazolinium nitrate |
Hill Formula | C14H15N3O3 |
HS Code | 2933 29 10 |
EC number | 225-915-4 |
Molar mass | 273.29 g/mol |
CAS number | 5144-52-5 |
Chemical and physical data | |
Solubility | 28 g/l (20 C) |
Melting point | 167 - 170 C |
Molar mass | 273.29 g/mol |
Bulk density | 550 kg/m3 |
pH value | 5.0 - 6.5 (10 g/l, H2O, 20 C) |
Safety information according to GHS | |
Hazard Statement(s) | H302: Harmful if swallowed. |
Signal Word | Warning |
Hazard Pictogram(s) | |
Storage class | 10 - 13 Other liquids and solids |
WGK | WGK 3 highly water endangering |
Disposal | 3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. |
Safety information | |
R Phrase | R 22 Harmful if swallowed. |
Categories of danger | harmful |
Hazard Symbol | Harmful |
Toxicological data | |
LD 50 oral | LD50 rat 1260 mg/kg |
Specifications | |
Assay (perchloric acid titration, calculated on dried substance) | 99.0 - 101.0 % |
Identity (IR-spectrum) | conforms |
Appearance | white or almost white, crystalline powder |
Appearance of solution (10 g/l, water) | clear and colourless |
pH (10 g/l, water) | 5.0 - 6.5 |
Chloride (Cl) | 0.02 % |
Residual solvents (Ph.Eur./USP/ICH) class 2 (Toluene) | 80 ppm |
Residual solvents (Ph.Eur./USP/ICH) class 3 (Acetone) | 1000 ppm |
Residual solvents (Ph. Eur./USP/ICH) of class 3 (Propan-2-ol) | 5000 ppm |
Diisopropylether | 500 ppm |
Other residual solvents (Ph. Eur./USP/ICH) | excluded by the manufacturing process |
Related substances (HPLC) - Naphthylacetylethylenediamine | 0.5 % |
- Largest unspecified impurity | 0.10 % |
- Sum of all impurities | 1.0 % |
Sulfated ash (600 C) | 0.1 % |
Loss on drying (105 C) | 0.5 % |
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